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Home > Learn about kidney disease > Polycystic Kidney Disease

Polycystic Kidney Disease

Polycystic Kidney Disease is a kind of hereditary disease caused by autosomal defect. Whether your condition still can be reversed? We will give the answer here.

Basic

PKD,called polycystic kidney disease,is a kind of hereditary disease caused by autosomal defect.
What is PKD?
PKD refers to many various cysts in renal parenchyma of both kidneys.Then the various cysts will be larger with the time going on and constrict the kidneys.What's worse,the bigger cysts will rupture and damage the kidneys,effecting the renal function.PKD has 2 types:ARPKD(Autosomal recessive polycystic kidney disease) and ADPKD(Autosomal Dominant Polycystic Kidney Disease).
What causes the polycystic kidney disease(PKD)?
The exact etiology of PKD is unclear. Although the symptoms appear in adulthood,the cysts often occur in foetal period.According to many studies,the abnormal cellular growth and changes as well as the intercellular substance that are caused by genetic defects are one of the most important causes of PKD.What's worse,as the time and disease progress,PKD will worsen into ESRF,which is the fourth reason.
Diagnosis
The diagnostic criteria of PKD can be divided into the main diagnostic evidence and auxiliary diagnostic evidence.
main diagnostic evidence
--numerous and unequal sized liquid cysts
--specific family history of ADPKD
--gene linkage analysis are positive
auxiliary diagnostic evidence
--polycystic liver
--renal insufficiency
--cysts on spleen or pancreas
--abnormal heart valve
--intracranial aneurysm
--ventral hernia
Some routine inspections,like CT,serum creatinine,urine routines,etc,play an very important role in diagnosed with PKD.
Prognosis
Owing to the heredity of PKD,there are no exact treatments to cure or stop the disease.So it is important to prevent the complications from appearing and stop the disease progressing.To controlling the high blood pressure,prevent the infections,and take a healthy diet are significant to delay the disease condition.
If you are diagnosed with PKD or you have other questions about your disease,you can contact with live doctor to get the professional guidance freely.

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Symptoms

PKD is caused by autosomal defect.,belonging to hereditary disease.In early stage,the size of kidneys is normal or slightly larger.With the time going on,the number is more and more and the size is bigger and bigger.Almost cases suffer from obvious and severe symptoms at the age of 40-50.Here are several symptoms for patients to take care of their health.
1.Ache of the back,waist and stomach
As the time and disease progress,the number and size of cysts are increasing,which may cause the constriction on patients' back or waist .Long-term walking,fatigue and overwork may worsen the disease condition.Besides,renal hemorrhage and renal stone are also the reason of sharp pain.
2.High blood pressure
It is the most primary symptom of PKD.Due to the damage on kidneys,renal function can not work effectively and timely,which causes the decline of renin.The reduced renin is closely related to the high blood pressure.What's worse,high blood pressure increase the risk of complications,which makes the prognosis of PKD patients is poor.
3.The infection of urinary tract
The cysts will be larger and larger with the time and patients condition progressing.One day,the cyst may brust in body,which will damage the kidneys and cause the urinary tract infection.At this time,hematuresis and burning or painful urination may occur.
4.Renal stone
The damaged kidneys can not work regularly and effectively,which may influence the acid-base balance.Unbalanced acid-base may lead to the renal stone being easier than in normal situation.
5.intracranial aneurysm
The damaged kidneys may increase the incidence rate of high blood pressure,which lead to the increased risk of intracranial aneurysm.
6.Gout
With the GFR reducing,the excretion of uric acid is reduced,which may lead to the increasing of the concentration of serum uric acid.
7.Hernia
In generally,hernia is one of the side-affects of dialysis,which increases the pain of patients.
Owing to the inexact pathogeny of PKD and the severe complications,it is much more important for patients with PKD to take early diagnosis and therapy.

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Diet

PKD(polycystic kidney disease) belongs to a kind of congenital genetic disease.For patients with PKD,the importance of healthy diet is more than the short-term clinical treatment.The enlargement of cysts is a result of many causes.So patients should pay more attention to those causes to control their disease condition and slow down the deterioration process of disease.
1.Some foods that are suitable to eat more
--vegetables or fruits are rich in high vitamin and iron.Such as carrot,radish and so on.
--Some foods are beneficial to dissolve the renal stone,like black agaric,etc.
--Alkaline diets are appropriate,which are effective to help the treatment,for example,cucumbers,green tea.
2.food prohibition
--Stop drinking and smoking
Liquor,especially the white spirits, will irritate the kidneys and promote the growth of cysts.So to stop drinking and smoking is very useful to control patients condition.
--Fermented foods
Fermented foods will expedite the growth of cysts,such as fermented bean curd.
--High vegetable protein
The shortage of protein lead to severe consequence of kidneys, so the supplement of protein is important.But the foods that are rich in high vegetable protein are not suitable to patients.The too much intake of vegetable protein will increase the renal burden and reduce the renal excretory capacity.Offering enough high quality protein is good for patients to control the condition and relieve the symptoms.
--offal products
Most offal products are not suitable for patients with PKD,especially the livers.Livers can detoxify the toxins in body.When animals are killed,metabolic toxins are left in livers.Then when patients eat livers,the damage on kidneys will be increased and worsen the disease.
Owing the different situations,the specific intake of foods should follow the doctors' guidance.If you have problems about your disease,you can contact onlive doctor to get the professional guidance freely.
Except the healthy diet,patients should cooperate with the doctor treatment actively.Furthermore,the main treatment is to control the complications and slow down the disease process.

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Treatment

Due to the uncertain cause and difficulty of PKD,there are no totally effective treatment to stop and cure the disease.So early detection and preventing the appearance and development of complications timely is very important.
Western Medicine
1.Control the high blood pressure
Hypertension is the most serious symptom of PKD,which may increase the renal burden and worsen the disease condition.So to control the high blood pressure is important to prevent the disease.Such as ACEI,ARB and Calcium Antagonists are used to control the high blood pressure.
2.Reduce the possibility of urinary tract infection
Infections increase the risk of disease progression and the pain of patients.So reduce the urinary tract infection is necessary.In this case,cranberry is beneficial to controlling the disease process.
3.Operation
For renal casts,paracentesis and renal cyst decortication are used frequently to relieve the clinical symptoms and reduce the blood pressure and protect the renal function.However,operation can not slove the problems completely and the disease may be easy to relapse.So doctors often advise patients take conservative treatment.
4.Dialysis and Renal Transplant
In later stage of disease,general therapies have been unable to control the disease process.Dialysis and Renal Transplant are taken to stop the disease.The effect of them is good but the side-effects are severer too.
Traditional Chinese Medicine
1.Chinese Medicine
Natural herbs are taken to control the disease and prevent the cysts from largening.Besides,some medicine is good for the renal repair and can also improve the renal function.
2.Micro-Chinese Medicine Osmotherapy
It is a type of external Chinese medicine,made by natural herbs.Compared with Western Medicine,Micro-Chinese Medicine Osmotherapy has less side affects.Moreover,it also does large impact on relieving the symptoms and prolonging the life-pan of patients as far as possible.
Dietotherapy
Healthy diet is important for patients to control the disease process.A low salt diet about 2-3g everyday is advisable.Furthermore,take a low protein,potassium and phosphorus diet.It is better to eat more proper vegetables to increase body resistance.

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Healthy Living

Due yo the chronicity and difficulty of PKD,there are no effective and unified treatments to cure the disease.What's worse,many cases may induce the cysts.So what should patients with PKD pay attention to in daily life?
1.Hold a optimistic mood
Scientific research shows that the cyst is the consequence of congenital and acquired reasons that can be changed or controlled to eliminate.So holding a optimistic mood is necessary,which can improve the body immunity and are beneficial to beat the disease.What's more,except the mood,patients should also cooperate with the treatment actively.
2.Take the scientific treatments
Scientific treatments are essential to treat the disease.Simple surgery can not cure the cysts completely even worsen the patients disease badly.So take the scientific treatments can control the disease effectively and relieve the symptoms.In addition,slow down the disease process as far as possible.
3.Do proper exercise to prevent cold and avoid the re-infection
Take proper exercise at proper time to increase the body immunity can reduce the risk of poor disease condition.Moreover,avoid the re-infection that may increase the renal burden and worsen patients condition,which are beneficial to patients condition and can also improve patients living quality.
4.Control the high blood pressure
The most majority of patients with PKD may suffer from the high blood pressure before the damaged renal function.What's worse,high blood pressure will worsen the renal function quickly and cause the damage on cardiovascular and cerebrovascular.Besides,it may also lead to some severe symptoms that may increase the risk of death.So controlling the high blood pressure can slow down the deterioration of renal damage and prevent the complications.
5.Keep a healthy diet
It is necessary to control the diet,Keep a low salt,protein and fat to reduce the risk of poor complications.Furthermore,high vitamin is good for patients.
Beyond that,if you have other questions about your condition,you can talk to online doctor or leave messages on below about your disease condition to get more detailed and professional guidance freely.

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