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Home > Learn about kidney disease > Purpura Nephritis

Purpura Nephritis

Purpura Nephritis refers to the damage on kidneys that is caused by HSP. Let's learn some basics and symptoms of Purpura Nephritishere.

Basic

Purpura Nephritis,called Henoch-Schonlein purpura nephritis,is caused by HSP (Henoch-Schonlein Purpura) with necrotizing vasculitis as the main pathological changes of systemic diseases
What's Purpura Nephritis?
Purpura Nephritis refers to the damage on kidneys that is caused by HSP that belongings to systemic diseases with necrotizing vasculitis as the main pathological changes.Except some symptoms like skin purpura, stomachache or hemafecia,hematuria and proteinuria may occur.Whats' worse,the lesions may damaged the renal function badly.The damage on kidneys usually appears within days to weeks after skin purpura.
What causes the Purpura Nephritis?
The reasons of Purpura Nephritis care some allergic reaction cause by infections of germ,virus or parasite.Besides,some foods and drugs may cause the allergy,which is also likely to produce Purpura Nephritis.
1.Infections
Some patients with Purpura Nephritis are usually diagnosed with URI(upper respiratory infection) before.
2.Drugs
Drugs like antibiotics,sulfonamides and captopril,may cause allergy,leading to Purpura Nephritis.
3.Foods
Sea foods are usually to effect the disease,like shrimp and crab diver.
4.Others
Pollens of plant,ova,oil paint and so on.
Diagnosis
The diagnosis of Purpura Nephritis must meet the the following three conditions:
1.There are some symptoms of skin purpura.
2.Some clinical symptoms of damaged kidneys,like proteinuria,high blood pressure and hematuria,etc.
3.Pathologic change tested by renal biopsy shows the deposition of IgA on mesangial area and mesangial proliferation.
Prognosis
The prognoses of Purpura Nephritis are very different owing to the level of disease condition.Patients with simple hematuria have a good prognosis.However,when various level proteinuria or NS and the progressive deterioration of renal function occur,the prognose are bad.

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Symptoms

Purpura Nephritis is a kind of secondary disease caused by HSP(Henoch-Schonlein Purpura).The damage of HSP will effect the kidneys within days to weeks after the appearance of skin purpura.So the symptoms of Purpura Nephritis occur outside and inside of kidneys.
1.extrarenal manifestations
--Rash
Rash is the first and main clinical manifestation.It often occurs in distal limbs,buttocks or lower abdomen and spreads symmetrically.What's more,it is slightly higher than the surface of the skin and patients may have itching too.Moreover,the time are usually 2 weeks that the purpura worsen into renal damage.
--Arthralgia
It is the common symptoms and often occurs in ankles.
--Gastrointestinal symptoms
Gastrointestinal symptoms is common to see.The clinical manifestations were mainly abdominal pain and diarrhea.Sometimes paroxysmal colic may occurs too.Besides,patients may suffer form nausea,emesis and bloody tool.
--Others
Except the common symptoms,lymphadenectasis and hepatosplenomegaly is visible accidentally.Moreover,nervous system will be influenced,thus patients will be headachy,convulsive and have abnormal behavior.
2.Renal manifestations
As the time and disease progress,the kidneys may be effected gradually,which mostly occurs in a few days to several weeks after the appearance of systemic signs and symptoms.
The main manifestation of kidneys are microscopic hematuria and proteinuria.Nearly half of the patients suffer from NS(Nephrotic Syndrome) and some patients have a decline of renal function.According to the studies,there is no obvious correlation between the severity of renal damage and degree of damage on skin, joints, gastrointestinal.What's more,high blood pressure will increase the risk of poor prognosis.
Except the above symptoms,there are some other unobvious symptoms.If you have been diagnosed with Purpura Nephritis or you want to more specific about your disease,you can talk to online doctor to get more detailed and professional advice and guidance.

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Diet

Purpura Nephritis is a type of secondary disease caused by HSP(Henoch-Schonlein purpura).The diet of renal disease has taboos,so does the patients with Purpura Nephritis.There are some rules that can help patients with Purpura Nephritis.
1.Control the intake of protein
Take high quality protein to offer the shortage of protein in blood.The low plasma proteins may reduce the body resistance and the infections are easy to occur.,which may worsen the disease condition.The 1g/kg intake of protein is advisable and high quality is the most important.
2.Limit the intake of salt and water
  When edema or high blood pressure appears, the intake of salt and water should be limited.Too much intake of salt will aggravate the retention of sodium and water,which will worsen the edema and increase the blood pressure.Besides,the intake of water should be controlled according to the urine volume and the degree of swelling.Generally speaking,the intake of water should be limited in 500ml-800ml every day.
3.Take fresh vegetables and fruits
It is beneficial to increase the body resistance for patients and avoid the infection.
4.Food prohibition
--Do not eat the allergenic foods that may worsen the disease and increase the renal burden.Such as fishes,shrimp and pollen,etc.
--Spicy food is not suitable to patients that may worsen the disease condition.
--Stop smoking and drinking.It will increase the renal burden and worsen the disease.
--Patients with high proteinuria should pay attention to the intake of protein and avoid increase the body burden.
Although we have cited many examples,the specific diet are not same as above.Patients should take foods follow the doctors' advice based on patients condition.If you want to get more professional guidance about your disease,you can contact the online doctor or leave messages ob below.

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Treatment

Due to the chronicity and secondary lesions of Purpura Nephritis,there is no effective treatment can cure the disease completely.The specific treatments are taken based on the patients condition.If you want to know which therapy is right for you,you can ask the online doctor to get the professional guidance freely about your disease.
1.The principle of treatment
Control the immune inflammatory response actively and inhibit the glomerular mesangial proliferative lesion to prevent and slow down the formation of lesion of renal chronic fibrosis.
2.General treatment
  Notice the rest and keep the balance of water and electrolyte.The patients with edema and massive proteinuria should take a low-salt,confining water intake and low-protein intake.Besides,prevent the upper respiratory infection (URI) and clean the chronic infection lesions and avoid the re -infection.
3.Drug treatment
Drug treatment is aimed at the specific symptoms.According to the changes in patients' conditions,taking the different medicine can the slove those problems.Such as ARB,ACEI and CTX,etc.However the use of western medicine have some side-affects that may worsen the renal disease badly.So take medicine must follow the doctors' advice.
4.Blood purification
When the disease are active,blood purification will make some difference to relieve the renal damage and delay the process of ESRF.
5.Dialysis and Renal Transplant
When the disease are worsen into later stage,dialysis and renal Transplant are necessary to control the disease process effectively.As an alternative therapy,dialysis can replace the part of renal function to keep the whole system in balance.Besides, renal Transplant is a efficient way to slove the renal disease.However,side affects of dialysis and renal Transplant are harmful to patients condition
6.TCM
Compare to the Western Medicine,TCM has less side affects.Micro-Chinese Medicine Osmotherapy,Blood Pollution Theory and Immunotherapy are beneficial to control the disease condition and relieve the symptoms timely and effectively.What's more,they can also ease the pain of disease,improve the physical function and quality of life.
That which method is suitable to you depends on your disease condition,if you are diagnosed with Purpura Nephritis,you can leave messages about your disease condition on below to get the professional guidance freely.

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Healthy Living

Purpura Nephritis is a kind of capillary allergic disease.It may effect the glomerular capillary and interstitial blood vessel,thus it may the renal damage with edema,proteinuria,hematuresis and abnormal renal function,etc.So what should patients pay attention to control the disease process?
1.Take enough rest and avoid fatigue to control the disease process.
Proper exercise will increase the body resistance and improve the immunity and prevent fatigue from worsening the renal damage.Besides,enough rest proper exercise can stabilize patients condition and improve the body functioning.
2.Be sure to keep warm and prevent the cold.
  Recurrence rate of Purpura Nephritis is high and the renal damage is easy to be worsen.So keep clean and prevent the infection play an important role in controlling the renal damage.
3.Take a healthy diet
Control the intake of salt and protein to delay the disease process and relieve the symptoms as far as possible.The decline of salt and water may reduce the level of edema and slow down the high blood pressure.The high quality protein is beneficial to patients condition,such as milk,lean meat and fishes,etc.
4.Insist on the scientific treatments
5.Take the scientific treatments
Scientific treatments are good for patients to control the disease and relieve the disease condition.Giving up the treatments optionally may worsen the disease badly even causes death.
6.Hold a optimistic mood
Avoid the fluctuation of mood and the mental stimulation which are good for patients to protect the patients state.A optimistic mood can strengthen body immunity and improve the confidence to beat the disease.
In general,Purpura Nephritis should be diagnosed and treated timely.Besides,avoid the re-infection to damage the kidneys.If you have other questions about your disease,you can contact with online doctor to get more guidance freely.

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