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Home > Learn about kidney disease > Membranous Nephropathy

Membranous Nephropathy

Membranous Nephropathy is more common among Caucasians, the disease occurs in all races. Let's learn more about it and find effective treatment here.

Basic

Membranous Nephropathy (MN) refers to a disorder that damages the kidneys' filters called glomeruli due to immune complex deposits within the kidney. It is one of the most common causes of Nephrotic Syndrome in adults. Over time, this can result in kidney failure as well.
The disease affects patients of all ages but it is more frequently diagnosed in middle age (40-50 years old). Although it is more common among Caucasians, the disease occurs in all races.
Diagnosis
A kidney biopsy is done to make a diagnosis of Membranous Nephropathy and to distinguish it from other disorders that may also lead to protein (and blood) losses in the urine.
Blood tests can be done to look for evidence of infections and autoimmune disorders that may be related with this kidney disease. Other screening tests like a chest x-ray and mammogram (in women) may be suggested by the doctor.
Prognosis
About 40% of patients diagnosed with this disease experience a spontaneous remission within 5 years, even without treatment. On average, 20 years after diagnosis, 1/3 of patients will be in complete remission, and 1/3 will have developed into end-stage renal disease (ESRD) and need dialysis or a kidney transplant. Those individuals that initially present over 1g/day of protein in urine for more than 6 months tend to do worse. Their kidney function usually decreases regardless of treatment.
Kidney transplant in Membranous Nephropathy
There is a 10-30% chance that the disease will recur in the transplanted kidney. In general, the recurrence will occur in the first two years after transplant.
At present, there are no specific treatments for recurrence MN in the transplant. Up to 50% of patients with recurrence of the disease will lose their kidney. About 10-15% of all patients with the disease will eventually lose the kidney.

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Symptoms

Membranous Nephropathy is a disorder that causes changes and inflammation of the kidney's filters known as glomeruli. The inflammation may result in problems with kidney function. Symptoms of the disease often begin slowly over time.
Swelling (edema)
Some individuals with this disease develop swelling or edema of the eyelids in the morning, and of the legs late in the day. This results from retention of sodium and fluid and this is what leads them to seek medical attention.
= Foamy or bubbly urine
This symptom occurs due to excessive protein leakage in the urine. In Membranous Nephropathy, the glomerular basement membrane become thickened. The thicker glomerular membrane does not work normally, and large amounts of protein are lost in the urine as a result.
High blood pressure
Normally, kidneys play a key role in keeping blood pressure under controlled. After getting impaired, they fail to function adequately to perform this function. Blood pressure level may become increased as renal function declines.
Fatigue
Feeling tired is common for people with kidney disease and is usually caused by anemia.
In addition, other symptoms of Membranous Nephropathy may also include loss of appetite, excessive urination at night, weight gain, itchy skin, etc.
The goal of treatment for Membranous Nephropathy is to reduce symptoms and slow down or even stop the progression of the disease. At present, the latest treatment for kidney disease is Blood Pollution Therapy. It is developed by the nation's renowned nephrologists after more than twenty years' study and clinical practice. Through taking this treatment in time, the disease will not progress in the future. In favorable cases, kidney damage can even be reversed successfully. To learn more information, please Contact Us.

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Diet

Membranous Nephropathy is an autoimmune kidney disorder in which the body's immune system mistakes the body's own cells for a foreign invader, and forms immune complexes within the kidneys. This causes the glomerular basement membrane to thicken, which diminishes their ability to filter blood. For patients with this kidney disorder, dietary changes play an important role.
Diet for Membranous Nephropathy
1.Regulate the protein intake.
For patients who experience symptoms of proteinuria, they need to limit their consumption of protein. A moderate protein intake of about 1g of protein per kilogram of body weight every day is recommended.
2.Decrease the consumption of sodium.
If patients are suffering from swelling or edema, a diet low in sodium should be followed. Consumption no more than 1,500mg of salt per day is recommended. Avoid processed foods and choose fresh foods instead. Stay away from canned foods, soups, chips, broths, and condiments.
3.Limit consumption of fat and cholesterol.
A diet low in fat and cholesterol should be taken to prevent further increase of cholesterol levels related with Membranous Nephropathy so as to reduce the risk of cardiovascular complications. Avoid saturated fats and foods high in cholesterol. This includes foods like eggs, whole milk, butter, fatty cuts of meats and fried foods.
The above gives general suggestions on diet for Membranous Nephropathy. Because each patient's condition is unique, it is always advisable to consult a dietitian for proper dietary arrangements. Want to know the most suitable meal plan in your case? You can Contact Us to get free and professional advice from our kidney experts team. Take care please!

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Treatment

When you are treated at Shijiazhuang Kidney Disease Hospital for Membranous Nephropathy, some of the nation's top nephrologists focus their expertise on you. The communicate with each other - and with you - to ensure you receive the most advanced treatment with no side effect to your body.
As one of the nation's leading Kidney Disease treatment centers, we see many more patients with Membranous Nephropathy than other clinics. This means we have a higher level of experience and expertise, which is crucial to your treatment and recovery.
If you are diagnosed with Membranous Nephropathy, your doctor will discuss the best options to treat it. This depends on several factors, including your stage of kidney disease, overall health condition, medical history, etc. Your treatment for MN will be customized to your particular needs. One or more of the following therapies may be recommended to treat your renal disease and eliminate symptoms.
Top Seven TCM Therapies
After over 20 years' research and clinical experiences, kidney experts of Shijiazhuang Kidney Disease Hospital have invented a series of traditional Chinese medicine remedies for kidney disease. They may include Hot Compress Therapy, enema, cycle therapy, moxibustion, oral Chinese herb medicine, full bath therapy and foot bath.
Based on each patient's specific diagnosis, doctors will chose specific treatment methods to form comprehensive treatment plan which can ensure the best curative effects. Want to learn more? Feel free to Contact Us.
Micro-Chinese Medicine Osmotherapy
Micro-Chinese Medicine Osmotherapy is a novel therapy which is developed on the basis of traditional Chinese medicine. Through external application of herb medicine, this treatment can function effectively to treat a variety of kidney diseases by expanding the blood vessels, promoting the blood circulation, inhibiting inflammatory response in the kidneys, degrading and removing harmful substances out of the body. With a favorable internal environment, renal damage can be repaired over time. Want to get evaluated for this therapy? Please consult our online doctor for free advice!
Blood Pollution Therapy
Different from conventional treatments, Blood Pollution Therapy combines advanced Blood Purification techniques and traditional Chinese medicine remedies. Through clearing up harmful substances out of the body and repair the impaired kidneys, overall renal function will be restored gradually.

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Healthy Living

Being diagnosed with Membranous Nephropathy can be a shocking and distressing experience. But have hope. You can live a satisfying life with kidney disease, just as millions of individuals are currently doing. Once you have accepted your condition and learned to lead a healthy lifestyle, you can go on to enjoy a normal life.
Do regular and proper physical activities.
This is an important part of living a well-balanced life. Having Membranous Nephropathy doesn't mean that you have to give up the fun things in life. Taking exercises is one way to keep your body strong and vital as well as help relieve stress and improve the sleep quality. Consult your health care team for the most suitable exercise program.
Stay positive.
A good attitude is vital for a good life. Empower yourself by being proactive about your disease. Learn all you can about Membranous Nephropathy and its management. Do the things you love to do. Visit your friends, go out to dinners and enjoy the fun of traveling.
Know about sexuality and fertility with kidney disease.
It is good to be aware that having kidney disease may affect your sex life. You may find you have less energy for sex and less interest in it. You should talk with your partner and explain that the changes in your body, and the resulting changes in self-image, are not a reflection of your feelings for your partner. Try other ways to express your feelings for your partner and maintain a sense of closeness.
If you are considering having a child, it's always advisable to firstly consult your kidney doctor to confirm that pregnancy will not aggravate your disease and are safe for you and your baby.

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