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Home > Learn about kidney disease > Lupus Nephritis > Lupus Nephritis Basics >

Lupus Nephritis: Clinical Symptoms & Diagnosis

2014-04-06 15:06

Lupus Nephritis(LN)is SLE combines with both kidneys immunity damage of various pathological patterns. Meanwhile, people experience obvious kidney damage in clinic. Its morbidity relates to form immune complex, dysimmunity of immune cell and cytokines. Nine out of 10 people with lupus are women. The disease usually strikes between age 15 and 45

Clinical symptoms

1. The whole body symptoms

Patients with LN present disconnected fever, erythema in pars zygomatica (butterfly erythema), discold erythema, photosensitization, dental ulcer, arthritis, orrhomeningitis, nervous system abnormal (tic and psychosis).

2. Renal manifestation

LN may present some symptoms of nephritis:

such as retinitis slimplex hematuresis or proteinuria, edema, soreness of waist and hypertension; nephritic syndrome manifestation, such as a large number of proteinuria, hypoproteinemia and edema; symptoms of acute nephritis, such as: hematuresis or proteinuria with kidney function slow down rapidly. In addition, patients may experience renal interstitium lesion or chronic renal failure. If you want to get a personalized analysis, you can email us at kidneyservice@hotmail.com.


If patients who are detected with SLE have above manifestation, Lupus Naphritis can be detected.

1. Pathology classify

Pathology classify of Lupus Nephritis can be divided into 6 type:

Type I: normal or minimal change disease.

Type II: mesentery proliferative

Type III: Frame proliferative

Type IV: pervade proliferative

Type V: membrane Lupus Nephritis

Type VI: hardenability

2. Renal pathology activity indicator:

(1) Glomerulus cell proliferative change

(2) Fibrin thanatosis and cell nucleus dissolve

(3) Cellularity crescent

(4) Platinum loop phenomenon and hyaloids thrombus

3. Chronicity

(1)Glomerular sclerosis

(2)Fibrous crescent

(3)Kidney tubules atrophy

(4)Renal interstitial fibrosis

By learning symptoms and diagnosis about Lupus Nephritis, you can detect symptoms early and ask a doctor timely.

Any kidney problems? Please consult our online doctor. The satisfaction of patient is as high as 93%.

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