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Home > Learn about kidney disease > Chronic Kidney Disease > CKD Treatment >

As A Kidney Disease Patient You Should Pay Attention to Metformin

2016-10-05 13:56

As A Kidney Disease Patient You Should Pay Attention to MetforminMetforimin is a common and effective western medicine for type 2 diabetes which can help control the high blood pressure, however, the research shows that this medicine have side effects in patients with kidney disease.

Recently, a research shows that metformin will not cause kidney damage for people with normal kidney function, in turn it can help protect the kidneys. The metformin has the function of protecting kidneys by the increased levels of a molescule known as AMPK (AMP Kinase). The research concerned an adipokine, a hormone produced by fat cells, which is called adiponectin. Different from other substances produced by fat cells, adiponectin is good for people, which can help suppress inflammations and reduce the amount of protein in urine. Besides, the adiponectin can activate AMPD, and when the AMPD is stimulated, the kidney will stop leaking protein. In this aspect, we can find that metformin can help protect the kidney function for people who have healthy kidneys.

However, for kidney disease patients, metformin may cause further kidney damage. Because metformin is excreted through kidneys, the damage kidney function cant discharge the wastes promptly, which will cause the metformin build up in kidneys. When the metformin in blood reaches a dangerous level, it will cause lactic acidosis, which is a dangerous condition with a high mortality rate. So kidney disease patients with diabetes should eat metformin following the advices of their doctors.

Besides, metformin can also cause side effects, such as gastrointestinal distress, which will affect people’s appetite. Patients can take metformin with meals, besides they can also take yogurt and milk thistle which can also remit their GI symptoms.

From the above, we can know that metformin can help protect the kidneys for healthy people, but it will cause damage to kidney disease patients. If you want to know more about the medicines of kidney disease or want to control this disease well, you can leave message to us, we will try our best to help you.

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Tag: Kidney Disease   CKD Treatment   Metformin  
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